Detection of Beta-Amyloid (Aβ) plaques in Alzheimer’s Disease (AD) using Immunohistochemistry (IHC) and image analysis was the subject of a recent publication in the Journal of Neuroscience Methods, 2011 (http://www.ncbi.nlm.nih.gov/pubmed/22019329) by Samaroo et al. at Pfizer. They applied a high throughput object-based image analysis methodology using Definiens software and validated it to quantify immunohistochemically stained β-Amyloid [...] Read more »